Molecule News and Research

RSS

St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Peptidomimetic antibiotics may be effective against resistant bacteria

Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers at the University of Zurich and the company Spexis have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.

1 Jun 2023

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.

31 May 2023

Important discovery could lead to new treatments for obesity and related diseases

Researchers at the University of East Anglia and the University of Cambridge have made an important discovery in the race to find treatments for obesity and related diseases, such as diabetes.

31 May 2023

UNIGE researchers identify how the influenza A virus manages to penetrate host cells

Influenza epidemics, caused by influenza A or B viruses, result in acute respiratory infection. They kill half a million people worldwide every year.

31 May 2023

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Evidence supports a close link between Aβ, astrocyte reactivity, and tau pathology in preclinical AD.

31 May 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

Experimental decoy provides long-term protection from SARS-Cov-2 infection

An experimental "decoy" provided long-term protection from infection by the pandemic virus in mice, a new study finds.

30 May 2023

Using generative AI to accelerate the drug development process

While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development process.

30 May 2023

New method to study the ultra-fast movements of proteins

Proteins are biological molecules that perform almost all biochemical tasks in all forms of life. In doing so, the tiny structures perform ultra-fast movements.

30 May 2023

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

A ground-breaking study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic drugs.

30 May 2023

Two key physiological systems found to be involved in high-salt-induced hypertension and dementia

Dementia is defined as the loss of cognitive functioning-;including thinking, remembering, and reasoning-;and is very prevalent in Japan.

29 May 2023

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

More than 40% of Americans are considered obese, and the trend continues to grow. The treatments or preventive options for obesity and obesity-associated diseases are limited.

26 May 2023

Hydrogen sulfide can be used to support photothermal therapy for cancer

Hydrogen sulfide is usually a highly toxic gas. However, with careful preparation, it can be used to support photothermal therapy (PTT) in treating cancer, as a team of researchers reporting in the journal Angewandte Chemie has recently discovered.

26 May 2023

Study highlights two strategies used by Salmonella to escape the human body's defenses

Like thieves that constantly look for ways to evade capture, Salmonella enterica, a disease-causing bacterium, uses various tactics to escape the human body's defence mechanisms.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Using an artificial intelligence algorithm, researchers at MIT and McMaster University have identified a new antibiotic that can kill a type of bacteria that is responsible for many drug-resistant infections.

25 May 2023

Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

LMU researchers have identified a signaling pathway via which curcumin can suppress the metastasis of colorectal cancer cells.

25 May 2023

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

A possible explanation has been found in a study for why apoE4, the most significant genetic risk factor associated with Alzheimer's disease, fails to protect the brain from inflammation.

25 May 2023

Molecule News and Research

St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Peptidomimetic antibiotics may be effective against resistant bacteria

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Important discovery could lead to new treatments for obesity and related diseases

UNIGE researchers identify how the influenza A virus manages to penetrate host cells

Biomarker study reveals the effects of astrocyte reactivity in preclinical Alzheimer's disease

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Experimental decoy provides long-term protection from SARS-Cov-2 infection

Using generative AI to accelerate the drug development process

New method to study the ultra-fast movements of proteins

Innovative probe could deepen our understanding of crucial cellular messenger and pave way for new therapeutic drugs

Two key physiological systems found to be involved in high-salt-induced hypertension and dementia

Study identifies a novel druggable signaling molecule involved in obesity and diabetes

Hydrogen sulfide can be used to support photothermal therapy for cancer

Study highlights two strategies used by Salmonella to escape the human body's defenses

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

Scientists use AI to identify new antibiotic that could fight drug-resistant infections

Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway

Alzheimer’s development: Study reveals why apoE4 gene fails to protect the brain from inflammation

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Latest News