Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Study measures the annual prevalence of nontuberculous mycobacterial lung disease in Ontario, Canada

Researchers determined the prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) in 2020.

1 Jun 2023

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Researchers reported on the treatment of rifampin-resistant tuberculosis in the United States using the FDA approved bedaquiline, pretomanid, and linezolid (BPaL) therapy.

1 Jun 2023

Can adherence to the Mediterranean diet reduce gestational stress and anxiety in pregnant women?

Researchers investigated the influence of structured Mediterranean diet intervention on the anxiety and stress levels.

1 Jun 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023

Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

Unlocking gut health: How indoor environment impacts the microbiota balance

Research paper highlights the importance of a diverse and balanced gut microbiota for human health, while emphasizing the need for further understanding of the impact of indoor microbiome and metabolites on gut microbiota.

21 May 2023

Food preservative nisin: A gut game changer that safely alters microbiome composition

Nisin, a powerful bacteriocin, influences the gut microbiota and its functionality by modulating the abundance of specific bacterial groups and altering short-chain fatty acid synthesis.

18 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Novel computational platform can expand the pool of cancer immunotherapy targets

Researchers at Children's Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor antigens derived from alternative RNA splicing, expanding the pool of cancer immunotherapy targets.

17 May 2023

Mass Spectrometry News and Research

Further Reading

Study measures the annual prevalence of nontuberculous mycobacterial lung disease in Ontario, Canada

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Can adherence to the Mediterranean diet reduce gestational stress and anxiety in pregnant women?

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Surviving without glucose: uridine-derived ribose as an alternative energy source

Unlocking gut health: How indoor environment impacts the microbiota balance

Food preservative nisin: A gut game changer that safely alters microbiome composition

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Novel computational platform can expand the pool of cancer immunotherapy targets

Molecular mechanism behind a DNA repair pathway revealed

H.E.L Group makes senior appointments as it continues to scale globally

Integrated proteomics approach identifies the contents of p62 bodies in detail

SARS-CoV-2 variants show altered glycan processing

Novel ingestible device enables non-invasive profiling of the gut microbiome, proteome, and metabolome

A machine-learning approach for the early diagnosis of Parkinson's disease

New antimicrobial coating material effectively kills bacteria and viruses

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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