Inflammatory Disease News and Research

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St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.

31 May 2023

Long-term consequences of COVID-19 in patients with inflammatory rheumatic diseases

Studies on the long-term consequences of COVID-19 (long-COVID) in patients with inflammatory rheumatic diseases (iRD) are scarce.

31 May 2023

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

To commemorate World Multiple Sclerosis (MS) Day, we speak to Dr. Cameron McAlpine about his latest research that sought to understand better the proteins and signals that act as messengers between brain and immune cells in MS.

30 May 2023

The drug company that prospered without creating any drugs

The new drug looked so promising — except for that one warning sign.

13 Apr 2023

Endometriosis linked to increased risk of cardiovascular disease in women

In a recent study published in the journal Maturitas, researchers conducted a systematic review and meta-analysis to compare the risk of cardiovascular events in women with and without endometriosis.

12 Apr 2023

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

Poor quality sleep may bolster a person's genetic susceptibility to asthma, potentially doubling their risk of being diagnosed with the condition, suggests a large UK Biobank study, published in the open access journal BMJ Open Respiratory Research.

4 Apr 2023

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

A team led by engineers at the University of California San Diego has developed a biodegradable polymer system to treat rheumatoid arthritis, an autoimmune and inflammatory disease, by working in concert with the power of the human immune system.

4 Apr 2023

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis.

22 Mar 2023

Does recurrent bacterial vaginosis impact quality of life?

A recent BMC Women's Health study performed a survey to understand how bacterial vaginosis affects women’s quality of life and what treatment they underwent.

22 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

C-reactive protein has a beneficial function in systemic lupus erythematosus

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

Study reveals a connection between arthritis flare-ups and periodontitis

Regular visits to the dentist might help keep joint pain at bay, too.

6 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Digital twins can lead to more personalized drug therapies for inflammatory diseases

Inflammatory diseases like rheumatoid arthritis have complex disease mechanisms that can differ from patient to patient with the same diagnosis.

28 Feb 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Researchers from the University of Washington (UW), Kenya Medical Research Institute (KEMRI), and Hennepin Healthcare Research Institute (HHRI) announced results at CROI from a clinical trial demonstrating that doxycycline taken after sex does not prevent bacterial sexually transmitted infections (STIs) – chlamydia or gonorrhea – among cisgender women.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

Inflammatory Disease News and Research

St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

NIH scientists identify genomic variants that cause rare inflammatory skin disorder

Long-term consequences of COVID-19 in patients with inflammatory rheumatic diseases

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

The drug company that prospered without creating any drugs

Endometriosis linked to increased risk of cardiovascular disease in women

Healthy sleep pattern may help offset asthma risk regardless of genetic susceptibility

UCSD engineers develop a biodegradable polymer system to treat rheumatoid arthritis

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Does recurrent bacterial vaginosis impact quality of life?

Study identifies link between oral and gut microbiomes and depression

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

C-reactive protein has a beneficial function in systemic lupus erythematosus

Study reveals a connection between arthritis flare-ups and periodontitis

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Digital twins can lead to more personalized drug therapies for inflammatory diseases

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Utilizing CRISPR to discover new therapy options for COPD

Breath Biopsy®: The Complete Guide eBook

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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