Neurodegenerative Diseases News and Research

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Environmental enrichment may reduce early accumulation of amyloid plaques in Alzheimer's mouse model

About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that could delay or prevent pathophysiological changes that occur with AD.

31 May 2023

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Astronauts are affected by various physical and chemical factors during spaceflight, resulting in a series of pathological and physiological changes.

30 May 2023

Researchers find oldest evidence of the plague in Britain to date

Researchers at the Francis Crick Institute have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague – the oldest evidence of the plague in Britain to date, reported in a paper published today in Nature Communications.

30 May 2023

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

To commemorate World Multiple Sclerosis (MS) Day, we speak to Dr. Cameron McAlpine about his latest research that sought to understand better the proteins and signals that act as messengers between brain and immune cells in MS.

30 May 2023

Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Tracking changes in blood vessels may hold clues to early detection of neurodegenerative diseases

While age-related brain disorders like Alzheimer's disease often develop slowly across an individual's lifetime, they usually aren't detected until symptoms have already started.

26 May 2023

Insights into the direction and extent of gut microbiome dysbiosis in Alzheimer’s disease and mild cognitive impairment

Researchers performed a meta-analysis to determine the association between intestinal microbiota and Alzheimer’s disease (AD).

26 May 2023

Superior cognition in individuals who are 90+ associated with resilience to neurodegenerative pathologies

A University of California, Irvine-led team of researchers have discovered that the oldest-old, those who live to be 90+ and have superior cognitive skills, have similar levels of brain pathology as Alzheimer's patients, however, they also have less brain pathology of other neurodegenerative diseases that cause memory and thinking problems.

25 May 2023

Researchers disclose how a nanomachine takes care of cleaning up inside the cell

To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly being disposed of.

25 May 2023

Gout unveiled as surprising culprit in neurodegenerative diseases

Research highlights the association between gout and neurodegenerative diseases, revealing that gout patients exhibit smaller brain volumes, increased brain iron markers, and a higher incidence of conditions such as dementia, Parkinson's disease, and essential tremor, particularly within the first three years after diagnosis.

22 May 2023

Researchers discover sex-specific genes, molecular pathways that contribute to Alzheimer's disease progression

Alzheimer's Disease (AD) is a complex neurodegenerative illness with genetic and environmental origins.

19 May 2023

Gamma frequency tactile stimulation can reduce Alzheimer's disease pathology and symptoms

Evidence that non-invasive sensory stimulation of 40 Hz gamma frequency brain rhythms can reduce Alzheimer's disease pathology and symptoms, already shown with light and sound by multiple research groups in mice and humans, now extends to tactile stimulation.

18 May 2023

New technique may reveal signs of Parkinson's disease in urine samples

A team led by researchers at Purdue University and Purdue spinoff company Tymora Analytical Operations has developed a technique that may reveal signs of Parkinson's disease in urine samples.

17 May 2023

New technique could mechanically enhance glymphatic transport in the mouse brain

Like the lymphatic system in the body, the glymphatic system in the brain clears metabolic waste and distributes nutrients and other important compounds.

16 May 2023

Researchers may have identified a molecular cause for memory changes in early childhood

How do our brains become capable of creating specific memories? In one of the first preclinical studies to examine memory development in youth, a research team at The Hospital for Sick Children (SickKids) may have identified a molecular cause for memory changes in early childhood.

16 May 2023

Neurodegenerative Diseases News and Research

Environmental enrichment may reduce early accumulation of amyloid plaques in Alzheimer's mouse model

Hydrogen inhalation provides a potential protective strategy for astronauts' brain health

Researchers find oldest evidence of the plague in Britain to date

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Novel assay for identifying individuals with synucleinopathies using serum samples

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Tracking changes in blood vessels may hold clues to early detection of neurodegenerative diseases

Insights into the direction and extent of gut microbiome dysbiosis in Alzheimer’s disease and mild cognitive impairment

Superior cognition in individuals who are 90+ associated with resilience to neurodegenerative pathologies

Researchers disclose how a nanomachine takes care of cleaning up inside the cell

Gout unveiled as surprising culprit in neurodegenerative diseases

Researchers discover sex-specific genes, molecular pathways that contribute to Alzheimer's disease progression

Gamma frequency tactile stimulation can reduce Alzheimer's disease pathology and symptoms

New technique may reveal signs of Parkinson's disease in urine samples

New technique could mechanically enhance glymphatic transport in the mouse brain

Researchers may have identified a molecular cause for memory changes in early childhood

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Menthol inhalation improves cognitive ability in animal models of Alzheimer's disease

Same genetic defects shared by some patients with motor neuron disease and frontotemporal dementia

Military personnel exposed to explosions show abnormal amyloid accumulation in the brain

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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