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UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Dr Philip Cardiff, Associate Professor at University College Dublin's School of Mechanical and Materials Engineering, has received a European Research Council (ERC) Consolidator grant of €2 million for his 5-year project XenoSim.

1 Jun 2023

Rheumatic and musculoskeletal diseases increase the risk of lethal comorbidities

Rheumatic and musculoskeletal diseases (RMDs) include over 200 diseases that affect over 120 million Europeans of all ages.

1 Jun 2023

SCORE2- diabetes prediction model estimates the 10 year risk of cardiovascular disease in individuals with type 2 diabetes

Researchers described the development and validation process of SCORE2-Diabetes.

1 Jun 2023

Multi-ethnic genome study unlocks new genetic links to health conditions

Research explores the genetic architecture of circulating metabolites, uncovering novel variant-metabolite associations and validating previous findings. It provides insights into the genetic contribution to metabolite levels and potential implications for human disease.

31 May 2023

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

Taurine and black pepper, along with key terpene constituents, are investigated for their potential in reducing cardiovascular risk factors and combating related diseases in this comprehensive literature review. Their cardioprotective effects and mechanisms are explored.

31 May 2023

Protein discovery could open up new treatment options for chronic kidney disease

Fresh insights into a protein that causes damage in kidneys and hearts could open up new treatment options for chronic kidney disease, research shows.

31 May 2023

Strengthening emergency, critical and operative care services in low and middle-income countries

Global efforts to improve emergency, critical and operative care for universal health coverage and protection from health emergencies were announced at the 76th World Health Assembly in Geneva, Switzerland.

31 May 2023

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Newborn babies who experience low levels of oxygen in their body tissues (hypoxia) due to sleep apnea, for example, tend to develop respiratory problems and hypertension (high blood pressure) in adulthood, and these problems may persist for the rest of their lives.

31 May 2023

Moderate-protein diet improves metabolic health in both young and middle-aged mice

Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers from Japan fed isocaloric diets with varying amounts of protein to young and middle-aged male mice.

31 May 2023

One-third of adults in the U.S. with Type 2 diabetes may have symptomless cardiovascular disease

1 in 3 adults with Type 2 diabetes may have undetected cardiovascular disease. Elevated levels of two protein biomarkers that indicate heart damage were associated with undetected or symptomless cardiovascular disease in adults with Type 2 diabetes compared to those without Type 2 diabetes, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

31 May 2023

Most American Indian/Alaska Native women of childbearing age have suboptimal heart health, AHA reports

Heart health risks emerge early in life in American Indian/Alaska Native (AI/AN) women and are increased by social factors -; like high levels of experiencing violence and traumatic life events -; and disproportionately high rates of Type 2 diabetes, smoking and obesity, according to a new scientific statement published today in Circulation: Cardiovascular Quality and Outcomes, a peer-reviewed American Heart Association journal.

31 May 2023

Smoking cessation among cancer survivors linked to lower cardiovascular risk

Cancer patients who continue smoking after their diagnosis have a nearly doubled risk of heart attack, stroke or death due to cardiovascular disease compared with non-smokers, according to research published on World No Tobacco Day in European Heart Journal, a journal of the European Society of Cardiology.

30 May 2023

Study finds significantly faster decline in cognition over the years after a heart attack

In a recent study, a Johns Hopkins Medicine researcher and collaborators analyzed data on adults to determine if there is a link between having a heart attack and cognitive decline.

30 May 2023

NJHF grants awards to two Kessler Foundation scientists to advance stroke, spinal cord injury research

Annually, New Jersey Health Foundation (NJHF) invites researchers to submit applications for grants aimed at supporting pilot research projects that exhibit promising potential.

30 May 2023

DNA test results may enhance prevention and treatment of alcohol use disorder

Today's substance use prevention efforts ignore individual genetic risk, but Rutgers research suggests DNA test results may eventually enhance prevention and treatment and improve outcomes.

30 May 2023

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

The low blood oxygen levels of obstructive sleep apnea cause widespread changes in gene activity throughout the day, according to a new study in the open-access journal PLOS Biology by David Smith of Cincinnati Children's Hospital Medical Center, US, and colleagues.

30 May 2023

Using generative AI to accelerate the drug development process

While it can take years for the pharmaceutical industry to create medicines capable of treating or curing human disease, a new study suggests that using generative artificial intelligence could vastly accelerate the drug-development process.

30 May 2023

Mutated gene protects the kidney from hypertension-induced damage

A mutation that causes severe hypertension also protects the kidneys from being damaged, reports a team led by Enno Klußmann of the Max Delbrück Center and the DZHK in "Kidney International".

30 May 2023

Researchers find oldest evidence of the plague in Britain to date

Researchers at the Francis Crick Institute have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague – the oldest evidence of the plague in Britain to date, reported in a paper published today in Nature Communications.

30 May 2023

RNA plays a role in regulating cell fate in the early mouse embryo

The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments.

30 May 2023

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Heart News and Research

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Rheumatic and musculoskeletal diseases increase the risk of lethal comorbidities

SCORE2- diabetes prediction model estimates the 10 year risk of cardiovascular disease in individuals with type 2 diabetes

Multi-ethnic genome study unlocks new genetic links to health conditions

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

Protein discovery could open up new treatment options for chronic kidney disease

Strengthening emergency, critical and operative care services in low and middle-income countries

Babies experiencing hypoxia due to sleep apnea tend to develop hypertension in adulthood

Moderate-protein diet improves metabolic health in both young and middle-aged mice

One-third of adults in the U.S. with Type 2 diabetes may have symptomless cardiovascular disease

Most American Indian/Alaska Native women of childbearing age have suboptimal heart health, AHA reports

Smoking cessation among cancer survivors linked to lower cardiovascular risk

Study finds significantly faster decline in cognition over the years after a heart attack

NJHF grants awards to two Kessler Foundation scientists to advance stroke, spinal cord injury research

DNA test results may enhance prevention and treatment of alcohol use disorder

Mice study shows how obstructive sleep apnea may affect gene activity throughout the day

Using generative AI to accelerate the drug development process

Mutated gene protects the kidney from hypertension-induced damage

Researchers find oldest evidence of the plague in Britain to date

RNA plays a role in regulating cell fate in the early mouse embryo

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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