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RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

1 Jun 2023

St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme.

1 Jun 2023

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and personalized medicine by enabling the efficient delivery of biomolecules for molecular repairs and genome remodeling.

1 Jun 2023

The debt ceiling deal takes a bite out of health programs. It could have been much worse.

Policy analysts, Democrats, and Republicans dissatisfied with the deal agree: Federal health programs have dodged a budgetary bullet in the Washington showdown over raising the nation's debt ceiling.

1 Jun 2023

New genetic risk factors for Alzheimer’s disease unique to Ashkenazi Jews identified

Alzheimer disease (AD), the most common neurodegenerative disorder in the world, affects individuals of all races and ethnicities; however, most genetic research for AD has been performed on individuals of European ancestry (EA) with a limited number of large-scale genetic studies in other populations.

1 Jun 2023

Recurrent cases of ocular toxoplasmosis more likely to occur in women

Women are more likely to experience recurrent cases of the Toxoplasma parasite, according to new Flinders University research.

1 Jun 2023

Long-term side effects of modern treatment for rheumatoid arthritis

Janus kinase inhibitors (JAKi) and biologics are the cornerstone of modern treatment for rheumatoid arthritis (RA). But there have been concerns over long-term side effects.

1 Jun 2023

EULAR launches unique resource of facts and figures related to RMDs across Europe

The European Alliance of Associations for Rheumatology (EULAR) is proud to announce the launch of RheumaFacts, an innovative and unique resource of facts and figures related to rheumatic and musculoskeletal diseases (RMDs) across Europe.

1 Jun 2023

EULAR announces the launch of new survey targeted directly at RMD patients

The European Alliance of Associations for Rheumatology has announced the launch of the EULAR Impact of RMDs Survey, an online questionnaire targeted directly at RMD patients.

1 Jun 2023

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles.

1 Jun 2023

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

Researchers from Children's Hospital of Philadelphia (CHOP) recently discovered that extremely thorough "deep sequencing" of the genome in tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies captured several genetic variants related to disease that were not captured with conventional genetic sequencing methods.

1 Jun 2023

New data guides treatment choices for patients with r/r lymphoma during pregnancy

Today, Blood Advances published a study revealing that patients with relapsed/refractory (r/r) lymphoma during pregnancy experienced a progression-free survival rate of 24% and an overall survival rate of 83%.

1 Jun 2023

Miniature video capsule shows capabilities like a traditional tube-based endoscopy

While ingestible video capsule endoscopes have been around for many years, the capsules have been limited by the fact that they could not be controlled by physicians.

1 Jun 2023

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Dr Philip Cardiff, Associate Professor at University College Dublin's School of Mechanical and Materials Engineering, has received a European Research Council (ERC) Consolidator grant of €2 million for his 5-year project XenoSim.

1 Jun 2023

Accounting for genetic factors can improve accuracy of prostate cancer screening

The accuracy of prostate-specific antigen (PSA) screening for prostate cancer can be improved by accounting for genetic factors that cause changes in PSA levels that are not associated with cancer, according to a multi-center study led by UC San Francisco and Stanford University.

1 Jun 2023

Rheumatic and musculoskeletal diseases increase the risk of lethal comorbidities

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Research News and Research

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

St. Jude discover NLRP12 as a direct bridge from hemolysis to inflammatory disease

Artificial viral vectors constructed from bacteriophage T4 show promise for advanced gene delivery

The debt ceiling deal takes a bite out of health programs. It could have been much worse.

New genetic risk factors for Alzheimer’s disease unique to Ashkenazi Jews identified

Recurrent cases of ocular toxoplasmosis more likely to occur in women

Long-term side effects of modern treatment for rheumatoid arthritis

EULAR launches unique resource of facts and figures related to RMDs across Europe

EULAR announces the launch of new survey targeted directly at RMD patients

Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

New data guides treatment choices for patients with r/r lymphoma during pregnancy

Miniature video capsule shows capabilities like a traditional tube-based endoscopy

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Accounting for genetic factors can improve accuracy of prostate cancer screening

Rheumatic and musculoskeletal diseases increase the risk of lethal comorbidities

Systematic approach needed to identify mental health issues in patients with inflammatory arthritis

Increased risk of cardiovascular disease in psoriatic arthritis patients

Working night shifts or binge drinking may be risk factors for COVID-19 infection among nurses

Key insights into immune responses after COVID-19 vaccination in Indigenous people

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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