HIV/AIDS - May 23, 2023 - Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

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	HIV/AIDS
	The latest HIV/AIDS news from News Medical

	Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

	Schlafen 12 identified as a novel HIV restriction factor An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor.

			Malaria: Developing Modern Vaccines for a Hard-to-Cure Disease This article outlines the challenges associated with curing malaria and stresses the importance of modern vaccine development for the treatment of the disease.

			Concomitant tuberculosis disease significantly impacts HIV immune responses in people with HIV New research from Boston Medical Center found that people living with HIV that have had pulmonary tuberculosis had broader and more potent HIV antibody responses and differences in HIV sequences predicted to be antibody resistant as compared to those without suspected or documented tuberculosis.

			Shortages of health workers strongly associated with higher death rates Shortages of health workers such as doctors, nurses and midwifery staff are strongly associated with higher death rates, especially for certain diseases such as neglected tropical diseases and malaria, pregnancy and birth complications, diabetes and kidney diseases, finds an analysis of 172 countries and territories, published by The BMJ today.

	Medicines for All Institute at VCU receives $18.7 million grant to improve access to medicines The Medicines for All Institute at Virginia Commonwealth University will work on 14 new global health projects and expand its capabilities to improve access to medicines around the world thanks to an $18.7 million grant from the Bill & Melinda Gates Foundation.

	Real-world assessment of JYNNEOS vaccine effectiveness during the 2022 mpox outbreak in the US A recent study published in Morbidity and Mortality Weekly Report estimated the efficacy of the JYNNEOS vaccine against mpox.

	Insight into next-generation protein therapeutics Next-generation protein therapeutics have become popular amongst researchers, especially after the emergence and development of novel COVID-19 vaccines, including mRNA vaccines, that thrust this concept into the spotlight at a global scale.

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