Mpox

Mpox is an exotic infectious disease caused by the Mpox virus. The disease was first identified in laboratory monkeys, thus earning its name, but in its natural state, it seems to infect rodents more than primates. A fever, headache, muscle pains, swollen lymph nodes, and fatigue are the first symptoms in humans. After this, a rash forms with blisters and crusts. Symptoms typically appear 7 to 14 days after exposure. In most cases, symptoms last 2 to 4 weeks. Children, pregnant women, and people with suppressed immune systems are at greater risk of severe cases.

Human Monkeypox – Epidemiology, Clinical Characteristics, Diagnosis, and Prevention

The human monkeypox virus, which belongs to the genus Orthopoxvirus of the family Poxviridae, is a DNA virus.

What is Monkeypox?

Monkeypox Epidemiology

Monkeypox 2003 U.S. Outbreak

Monkeypox; What is It and How Do We Treat It?

Latest Mpox News and Research

Wastewater data unveils underreported Mpox cases in Texas

A recent study characterizes the analytical sensitivity of three assays used to detect MPXV in wastewater samples.

31 May 2023

Mpox incidence across rural and urban areas in the US

Researchers explored the differences in rural and urban mpox incidence in the United States (US).

31 May 2023

CDC reports on its Mpox response

Research paper provides an overview of the U.S. monkeypox outbreak, highlighting the rapid response, vaccination efforts, and racial disparities in cases. Ongoing surveillance, vaccination, and communication are emphasized as crucial for future prevention.

24 May 2023

JYNNEOS vaccine shows strong effectiveness against Mpox in New York outbreak

In the recent Morbidity and Mortality Weekly Report (MMWR) published by the Centers for Disease Control and Prevention (CDC), researchers reported on JYNNEOS vaccine effectiveness (VE) against Mpox infections among New York (NY) residents in 2022.

23 May 2023

Real-world assessment of JYNNEOS vaccine effectiveness during the 2022 mpox outbreak in the US

A recent study published in Morbidity and Mortality Weekly Report estimated the efficacy of the JYNNEOS vaccine against mpox.

22 May 2023

Wastewater surveillance reveals hidden scale of mpox rpidemic, challenging official figures

Research highlights the potential of wastewater-based epidemiology as a complementary tool to clinical monitoring for assessing the magnitude of a mpox epidemic. Findings suggest that the presence of mpox DNA in wastewater does not directly correspond to the number of hospitalizations, indicating the underestimation of the epidemic's scale and unidentified cases.

19 May 2023

Understanding the adverse events profile of MVA-BN vaccine for Mpox

Researchers evaluated adverse events following the Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccination for mpox.

10 May 2023

A multisectoral, global, and interdisciplinary approach is needed for better pandemic preparedness

Researchers reviewed existing data on pandemics and described the steps needed to prevent the emergence.

4 May 2023

HIV status does not affect Tecovirimat treatment outcomes for Mpox virus infection

A retrospective cohort study comparing the clinical presentation and treatment outcomes of people with HIV and those without HIV who were treated with tecovirimat for confirmed mpox virus infection. The study found that HIV status did not seem to affect treatment outcomes.

4 May 2023

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

Researchers demonstrate that T helper 1 effector memory cluster of differentiation 4 T cells provide immunity against poxviruses

27 Apr 2023

GW one of 18 clinical trial sites across the United States testing monkeypox vaccine in adolescents

The National Institutes of Health trial to evaluate the mpox (previously known as monkeypox) vaccine JYNNEOS has now entered the next stage and is studying the immune responses to and the safety of the vaccine in adolescents.

19 Apr 2023

A judicial body blow to the ACA

Opponents of the Affordable Care Act may have stopped trying to overturn the entire law in court, but they have not stopped challenging pieces of it — and they have found an ally in Fort Worth, Texas: U.S. District Judge Reed O'Connor.

30 Mar 2023

Global mapping of bushmeat activity to improve zoonotic spillover surveillance

Researchers use geospatial models based to predict the rural global areas of bushmeat activity.

28 Mar 2023

Misleading and low-quality Mpox health information in TikTok videos

Researchers analyze TikTok videos on mpox for their content, information quality, and engagement.

21 Mar 2023

Efficacy of a single dose of MVA-BN smallpox vaccine against Mpox

A recent The Lancet Infectious Disease study focussed on estimating the effectiveness of a single dose of MVA-BN against Mpox in England. This observational study was conducted following the large-scale vaccination program that immunized the GBMSM group with the MVA-BN vaccine.

15 Mar 2023

Summarizing the evidence of respiratory transmission of mpox

A recent study published in The Lancet Microbe summarized the evidence for respiratory transmission of mpox (formerly monkeypox).

13 Mar 2023

Estimation of incubation period and serial interval of mpox virus infections in the United States

In a recent study, researchers determined the mean incubation period and the serial interval estimates of the mpox virus.

7 Mar 2023

CDC recommendations and clinical considerations for the treatment of severe Mpox

In a recent article published in the United States (U.S.) Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report, a team of researchers discussed the medical countermeasures and clinical considerations for treating severe manifestations of Mpox.

6 Mar 2023

Exploring Mpox severity among advanced HIV patients

Researchers assessed the incidence of mpox in individuals with advanced human immunodeficiency virus (HIV) infection.

24 Feb 2023

Study shows synergistic effects of vaccination and behavioral changes against monkeypox

In a recent study posted to the medRxiv* preprint server, researchers used mathematical modeling to estimate the averted number of monkeypox (MPX) virus (MPXV) infections due to interventions such as vaccination and lowered sexual partners.

15 Feb 2023

Mpox

Overview

What is Monkeypox?

Monkeypox Epidemiology

Monkeypox 2003 U.S. Outbreak

Feature Articles

Monkeypox; What is It and How Do We Treat It?

Latest Mpox News and Research

Wastewater data unveils underreported Mpox cases in Texas

Mpox incidence across rural and urban areas in the US

CDC reports on its Mpox response

JYNNEOS vaccine shows strong effectiveness against Mpox in New York outbreak

Real-world assessment of JYNNEOS vaccine effectiveness during the 2022 mpox outbreak in the US

Wastewater surveillance reveals hidden scale of mpox rpidemic, challenging official figures

Understanding the adverse events profile of MVA-BN vaccine for Mpox

A multisectoral, global, and interdisciplinary approach is needed for better pandemic preparedness

HIV status does not affect Tecovirimat treatment outcomes for Mpox virus infection

Research identifies Th1 memory CD4+ T cells as key to protect against emerging poxvirus skin infections

GW one of 18 clinical trial sites across the United States testing monkeypox vaccine in adolescents

A judicial body blow to the ACA

Global mapping of bushmeat activity to improve zoonotic spillover surveillance

Misleading and low-quality Mpox health information in TikTok videos

Efficacy of a single dose of MVA-BN smallpox vaccine against Mpox

Summarizing the evidence of respiratory transmission of mpox

Estimation of incubation period and serial interval of mpox virus infections in the United States

CDC recommendations and clinical considerations for the treatment of severe Mpox

Exploring Mpox severity among advanced HIV patients

Study shows synergistic effects of vaccination and behavioral changes against monkeypox

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Mpox

Overview

Feature Articles

Monkeypox; What is It and How Do We Treat It?

Latest Mpox News and Research

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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