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Oxygen restriction associated with longer lifespan in lab mice

For the first time, researchers have shown that reduced oxygen intake, or "oxygen restriction", is associated with longer lifespan in lab mice, highlighting its anti-aging potential.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Academic paper: AI is advantageous in all aspects of new drug research and development

Scientists have long been challenged by the complex process of drug discovery and development, with investments that often go unrewarded.

23 May 2023

$Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride$

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

For pharmaceuticals, knowing the chemical composition is not enough-;molecular geometry and crystal structure also play an important role in a drug's activity.

23 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Contraception ends same-sex sexual behavior’s genetic maintenance in modern societies

Evolution depends on genes being passed down through the generations via reproduction, and same-sex sexual behavior does not result in offspring.

23 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

Productive, error-free 2D tube rack reading

Ziath, an Azenta Life sciences company. reports that the high-speed of reading and error-free decoding offered by their DataPaq™ Mirage 2D tube rack reader, around 1 second for a full 96 position rack, has made it the instrument of choice for many life science labs.

From Ziath Ltd 23 May 2023

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

22 May 2023

Newly developed method can help identify the special differences in genetic information

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

22 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023

Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

Understanding the cause for suboptimal germinal center response in aged mice

Understanding the ways our immune response changes as we age holds the key to designing better vaccines and boosting protection for people most at risk.

22 May 2023

Dad’s genome may be playing a bigger role in siblings born with ASD

Cold Spring Harbor Laboratory researchers have flipped the script on autism spectrum disorder (ASD) genetics.

22 May 2023

Honokiol inhibits replication of SARS-CoV-2 in several cell types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

22 May 2023

AI-based method predicts small molecule substrates of enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

Exploring how and why nitrate has contrasting potential risks and benefits

Despite our understanding of nutrition expanding remarkably in recent times, few aspects of our diet continue to confuse and divide the experts like nitrate.

22 May 2023

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19.

22 May 2023

The State of Tech Bio: Survey finds majority of biodevelopers write code and use machine learning; protein engineering is a top priority

Cradle, the platform that helps scientists to design and program proteins, today published the findings of its first BioDeveloper survey, exploring the methods and priorities of biodevelopers to build a picture of trends within the synthetic biology sector.

From Cradle Bio B.V. 22 May 2023

Life Science News

Oxygen restriction associated with longer lifespan in lab mice

Looking at cancer drugs to help put the brakes on classic indicators of aging

Academic paper: AI is advantageous in all aspects of new drug research and development

Using 3D-electron diffraction to determine the structure of Levocetirizine dihydrochloride

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Contraception ends same-sex sexual behavior’s genetic maintenance in modern societies

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Productive, error-free 2D tube rack reading

Cytoelectric Coupling hypothesis: Fluctuating electric fields shape the brain’s molecular infrastructure

Newly developed method can help identify the special differences in genetic information

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Surviving without glucose: uridine-derived ribose as an alternative energy source

Understanding the cause for suboptimal germinal center response in aged mice

Dad’s genome may be playing a bigger role in siblings born with ASD

Honokiol inhibits replication of SARS-CoV-2 in several cell types

AI-based method predicts small molecule substrates of enzymes

Newly discovered molecule effectively destroys senescent cells

Exploring how and why nitrate has contrasting potential risks and benefits

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

The State of Tech Bio: Survey finds majority of biodevelopers write code and use machine learning; protein engineering is a top priority

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

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